We are soon entering the final week of the 2025-26 men’s college basketball regular season.
With the calendar flipping to March, all eyes are on who can win the national championship this season. Florida ― the defending national champions ― seems poised to make a run at a repeat, but No. 1 Duke, Michigan and Arizona are among the favorites who can make a run.
However, the field goes beyond those four teams. There are a handful of other programs that have a legitimate chance to hoist the trophy this season.
Here’s a look at the top 20 teams with the best odds of winning the national championship:
March Madness power rankings: Ranking top 20 teams based on odds
Odds courtesy of BetMGM as of 9:30 p.m. ET Saturday, Feb. 28
Despite a loss to Duke last weekend, Michigan is the odds-on-favorite to win the national championship this season at +325. However, the Blue Devils are a close second (+375), with Arizona (+425) and Houston (+950) right on their heels.
Defending national champion Florida is seeking to repeat, as UConn just did (the Huskies winning it all in 2023 and 2024). The Gators could join UCLA as the only program to ever win back-to-back championships twice.
1. Michigan, +325
2. Duke, +375
3. Arizona, +425
4. Houston, +950
5. Florida, +1000
6. UConn, +1300
7. Illinois, +1400
8. Iowa State, +1600
T-9. Kansas, +3000
T-9. Purdue, +3000
T-11. Gonzaga, +4000
T-11. Michigan State, +4000
T-13. Alabama, +6600
T-13. Arkansas, +6600
T-13. Nebraska, +6600
T-13. Tennessee, +6600
T-13. Virginia, +6600
T-18. St. John’s, +8000
T-18. UNC, +8000
20. Louisville, +9000