Week 10 of the 2025 NFL season begins with the Denver Broncos hosting the Las Vegas Raiders.
The NFL’s first regular-season game in Berlin will feature the Indianapolis Colts and the Atlanta Falcons.
Other key matchups include the Tampa Bay Buccaneers versus the New England Patriots and a Sunday night game between the Pittsburgh Steelers and the Los Angeles Chargers.
The second half of the 2025 NFL season kicks off Thursday when the Denver Broncos host the Las Vegas Raiders to ring in Week 10. Can’t, uh, wait for that one.
However the penultimate installment of this year’s International Series carries unexpected appeal, the (presently) top-seeded Indianapolis Colts and Atlanta Falcons meeting for the league’s first-ever regular-season game in Berlin in what could be recently acquired CB Sauce Gardner’s first game with Indy. Sunday’s lower-key game of the day might actually be a showdown of first-place teams when the Tampa Bay Buccaneers come off their bye to welcome the New England Patriots. ‘Sunday Night Football’ will pair the Pittsburgh Steelers and Chargers in Los Angeles.
But the most appealing and high-profile contest of Week 10 seems like Monday night’s matchup between the Philadelphia Eagles and Green Bay Packers from Lambeau Field in another ‘Love Hurts’ fixture that could be an NFC championship game preview. It will be the clubs’ third meeting since the start of the 2024 season, the Pack unable to notch a W in the first two − one in Brazil, the other a playoff loss at Philly.
Here’s how USA TODAY Sports’ panel of NFL experts forecasts the rundown:
(Odds provided by BetMGM)
NFL Week 10 picks, predictions odds
Raiders at Broncos
Falcons at Colts
Bills at Dolphins
Giants at Bears
Saints at Panthers
Browns at Jets
Jaguars at Texans
Patriots at Buccaneers
Ravens at Vikings
Cardinals at Seahawks
Lions at Commanders
Rams at 49ers
Steelers at Chargers
Eagles at Packers